The toolset is written in C# and requires the .NET Framework to run. However, this only applies to the toolset itself. The installation packages you create with the toolset do not require any extra framework or software to be installed on the target computer. Similarly, there might be a few additional utilities required for some special applications (merge modules, patches) but only on your build computer, the client will only need the finished and self-contained installer package, nothing else.
However, this lack of creative control can be frustrating. Wix ADI is not nearly as flexible as Wix Editor, which offers smooth drag-and-drop design and easily editable text boxes. So, while you can enjoy simplicity with both Wix tools, the Wix Editor offers more freedom. It also builds more personal sites, thanks to its Premium plan upgrades and wide choice of apps.